Bench To Bedside

Bench to Bedside Outline
A. What is bench to bedside look for?
* Described as test and error process where physician researchers find new research in the laboratory and then do clinical trials on patients
* Most of these patients be not humans initially; researchers unremarkably tests on animals first before injecting the dose into human patients
B. What are some types of bench to bedside research?
* Basic research- they analyze jail cell structure of cells and try to determine whether they are cancer cells or not. If they find some strange they send it to…
* Preclinical- is the actual work that is through in the lab. There are two types of preclinical research called in vitro and in vivo.
* In vitro means in glass; tests using cell lines and/or cell cultures contained in petri dishes and test tubes
* In vivo means exam without glass; testing on animals and collect information about the activity of the drug ( cognise as pharmocodynamic testing), as well as absorption, distribution, excretion known as (pharmacokinetic testing) and toxicity.
C. What are the trials of bench to bedside research?
* bod 1- judge the drugs and do research. Find out what dose of the drug is uninjured and how it should be given.




* Phase 2- the trial and error part; appreciate the drug and take quantitative Is the drug effective? Does it fill further testing? Finalize the dose if these questions have been answered.
* Phase 3- Tie the research together. Look at predicted results and final results. rate the efficiency toward the standard of care. Then confirm or deny the dose.
D. What are some examples of bench to bedside research being done?
* One of the first examples that was used for bench to bedside research was Anti-angiogensis
* Folkman who make his idea in 1971, but it wasnt until 2002 that Avastin, the VEGF inhibitior was approved for treating colon cancer
* UGA researchers actually found a new treatment for...If you deficiency to get a full essay, order it on our website: Orderessay



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