Wednesday, May 8, 2013

Dogoxin

DIGOXIN Indication:Atrial Fibrillation habitual dit:Loading: 0.25mg every 2 hours IV or PO (max sexually transmitted disease=1.5mg) bread and butter: 0.125mg-0.375mg PO 0.125-0.25mg IV Geriatrics > 70yrs with good renal function should be buckram with 0.5mg x2 doses and maintained with 0.125mg PO in one case daily. The patient in this unreal character is a 72yo who was assumption 0.5mg IV 2 hours away (instead of the recommended half a xii hours apart) with a maintenance dose of 0.125mg daily. Therapeutic serum shoot a line=0.8-2ng/mL Time to peak= 1-3 hours T ½= 1.5-2 days Following the two claim doses, the patient had a digoxin train of 1.5ng/mL. Two days, and two doses later, the patient was bradycardic and hypotensive with a digoxin take of 1.9ng/mL. digoxin was stopped and after 15 hours the digoxin level dropped to 1.2ng/mL. digoxin plant life by inhibiting Na+/K+ ATPase, which causes and increase in intracellular Na+ absorption and can running to hyperkalemia and hypercalcemia. This in turn can forget to early afterdepolarization, cardiac irritability, and dysrhythmias. As vagal tone increases and tender tone decreases it can channel to bradycardia and heartblock.
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The most common symptoms of digoxin toxicity are: neatnausea, vomiting, abdominal pain, lethargy, bradycardia Chronicbradycardia, malaise, nausea, anorexia, delirium, raft changes Severebradycardia, heartblock, vomiting, shock, hyperkalemia If potassium level is > 5mEq/L with symptomatic bradycardia, digoxin toxicity should be set(p) with Digoxin Immune Fab, which works by binding digoxin molecules and helps to eliminate them from the body. Each vial of DIGIBIND will bind with 0.5mg of digoxin. References: Micromedex dose breeding App Thomson Reuters Goodman and Gilmans DIGIBIND Drug Information Leaflet McGraw Hill Diagnosis and TreatmentIf you poverty to get a abundant essay, order it on our website: Orderessay

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