Promethazine

Laboratory Report # 3.2 Title:         Promethazine 0.2% Syrup          see:                   learner Name: 1.         Describe the dispensing directions for the preparation:         A. Indication and expect motion:                           Promethazine HCL is a powerful antihistamine drug employ to track allergic conditions and,                  because of the sedative action, insomnia. It is also utilize as an anti-tussive in cough mixings.         Promethazine can be administered by emit or injection.         B. Directions/administration/use: Sig:         TAKE wiz teaspoonful OF SYRUP BY MOUTH AT MEALTIMES AND AT BEDTIME.         C. Precautions/DI: elapse medication out of r distributively of children Do non confuse alcohol while on this medica tion Contraindications: ·         children below 2yrs ·         SC or intra-arterial injection ·         narrow-angle glaucoma ·         prostatic hypertrophy ·          vesica or pyeloduodenal obstruction ·         MAOI therapy ·         hypersensitivity to promethazine and other phenothiazines unseemly Reactions: drowsiness dizziness ·         xerostomia ·          purposelesspyramidal reactions                  Drug Interactions: belladonna benztropine cabergoline cisapride dofetilide gatifloxacin grepafloxacin halofantrine levofloxacin atomic number 3 meperidine hydrochloride moxifloxacin orphenadrine pimozide porfimer procyclidine sotalol sparfloxacin tramadol trihexyphenidyl          D. Storage: Keep the sirup at means temperature, away from heat, light, and moisture. Do not freeze.      Â Â Â Â E. miss paneling: Use your medi! cine as soon as you commend that you have missed your pane of glass. If it is nearly time for your side by side(p) dose, hold back until whence to use the medicine and write out the missed dose. You should not use two doses at unrivalled time. 2.         Purpose of each excipient used in the experiment: sweltry chocolate         -         flavoring mover Sucrose         -         sweetening component, suspending and viscosity-increasing agent. watery Glucose         -         to fork out calories, taste, and to improve cristal of atomic number 11                                    and water across the intestinal barrier through osmosis          Glycerin         -         used as a demulcent in cough preparations for soothing and protecting                            the mucous membranes and relieves irritation. When administered by                            backtalk or parenterally, glycerine increases the plasma osmolality,                           resulting in the movement of water by osmosis from the extra vascular                           spaces into the plasma. sodium Chloride-         electrolyte - source of sodium (Na+), used in combination with glucose for oral rehydration in shrewd diarrhea. Vanillin         -         flavoring/perfuming agent Sodium Benzoate         preservative with antibacterial and anti-fungal properties complete(a) Water         -         diluent 3.          draw your calculations and compounding (in steps):         Calculations: Promethazine HCL         2 g          Â!  Â Â Â Â Â Â Â x         (90mL / yardmL)         =         0.18 g Cocoa         180 g         x         (90mL / 1000mL)         =         16.

2 g Sucrose         600 g         x         (90mL / 1000mL)         =         54 g Liquid Glucose         180 g         x         (90mL / 1000mL)         =         16.2 g Glycerin         50 mL         x         (90mL / 1000mL)         =         4.5 mL x (1.25g/mL) = 5.625 g Sodium Chloride         2.0 g         x         (90mL / 1000mL)         =         0.18g sp. gravity Vanillin         0.2 g         x         (90mL / 1000mL)         =         0.018 g Sodium Benzoate         1.0 g         x         (90mL / 1000mL)         =         0.09 g P. Water         1000 mL         x         (90mL / 1000mL)         =         90 mL Ft. 90 mL         Promethazine:         (2 g / 1000 mL)         x 100 % = 0.2% sirup         1 Tsp = 5 mL x (0.2 % / 100 %) = 0.01 g x (1000 mg / 1 g) = 10 mg / dose Preparation: The sucrose and cocoa were merge together in a beaker. To this smorgasbord, the glu cose, glycerin and vanillin were gradually added. Th! e sodium benzoate and sodium chloride were indeed dissolved in a undersize amount (30 mL) of hot water. The promethazine HCL was then added to the solution and was complex well. The contents were then transferred to the mixture in the beaker. The entire mixture was brought to a moil and the boiling temperature was maintained for 2 minutes. The mixture was allowed to cool to room temperature and the volume was brought up to 90 mL by adding additive pure water. If you want to get a full essay, revisal it on our website: OrderEssay.net

If you want to get a full information about our service, visit our page: write my essay