Acetaminophen: How Much Do You Really Know About It?

acetaminophen: How much do you really know almost it?
Introduction
acetaminophen is very popular and is regularly used as a non-prescription drug to relieve pain caused by a wide variety of symptoms such as headaches, muscle and word pains, or menstrual cramps. 1
Discovery and History
Papa-aminophenol was observe in the easy 1800s and is a parent compound of acetaminophen and acetophenetidin.1 It was discovered that papa-aminophenol could reduce fever, however it was highly toxic. 1 It was discovered briefly after that acetophenetidin was much slight toxic and was skilful to be used medically. 1 It was also found to be antipyretic (fever-reducing) and was also a good pain-reliever so it became a popular medicinal drug to relieve both fever and pain. In 1949 it was discovered that the body converts acetophenetidin into an even less toxic substance called acetaminophen. 1 After this discovery, acetaminophen began to switch the now popular acetophenetidin as an analgesic (painkiller).1

chemic Structure
The chemical formula of the acetaminophen molecule is C8H9NO2.2 Its IUPAC name is N-(4-hydroxyphenyl)acetamide.2 Acetaminophen contains a benzine ring core, with a hydroxyl gathering and an amide group attached in the para pattern.



3 The amide group is ethanamide and is attached to the benzene ring by the nitrogen atom. 3 The nose candy atoms of the benzene ring all have atoms stick arounded in the same plane at about 120 degrees from separately other.4 This VSEPR shape is known as rhombohedral planar. 4 The hydroxyl group has a bent tetrahedral shape because of the two solitary pairs on the oxygen atom. 4 The nitrogen atom that attaches the benzene ring to the amide group has a tetrahedral shape, but since there is a lone pair present, the attached atoms form a trigonal pyramidal shape.4 The carbon at the end of the amide group has a tetrahedral shape with a hydrogen bonded at each site.4 The carbon in the middle of the amide group has a single bond between the nitrogen atom and the other...If you want to get a full essay, order it on our website: Orderessay



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